We were once carefree below-the-line film and TV workers: I did props and set dressing and Dave was an Assistant Director and occasional actor. Then we were thrust into family caregiving when my mom was suddenly diagnosed with Alzheimer’s Disease. We learned so much from my mother’s decade-long journey that I felt we had to share our best practices with other families in crisis. We created AlzNotes.com to provide care gap training and plant based education to others in relationship with dementia. My mom transitioned to Pure Positive Energy in 2019.
Cannabis Helps Dementia podcast was born out of my desire to shout from the rooftops how we and others have eased the suffering of loved ones living with dementia by using a medicinal herb where there is no other relief available. You’ll hear the science and stories of how cannabis helps ease the difficult behavioral symptoms caused by dementing illnesses.
One of the things we learned on this life-changing journey was that the United States Department of Health has held a patent since 1998 specifically for neuroprotection which inspired us to do more research.
Patent # 6630507B1 “…cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and HIV dementia…”
When we started to get serious about this research, we learned about Dr. Ethan Russo, who is a world renowned neurologist, psychopharmacology researcher, former Senior Medical Advisor to GW Pharmaceuticals (GW created Epidiolex and Sativex, cannabis based medications for epilepsy and MS symptoms) and he is a member of the Society of Cannabis Clinicians.
Dr. Russo is a badass rockstar of medical cannabis research and among many other things, he wrote a review article in Frontiers in Integrative Neuroscience, “Cannabis Therapeutics and the Future of Neurology” that really got my attention. Dr. Russo gives the reader an introduction to cannabis medicine, then shows us the studies that have already been done that show how cannabis helps multiple neurological issues including epilepsy, brain tumors, traumatic brain injury, Parkinson’s Disease and of course, Alzheimer’s.
We hope you like EP1 with Dr. Russo.
Please share, subscribe, rate and review to learn more about how cannabis helps dementia.
Dr. Ethan Russo
Society of Cannabis Clinicians
“The Scientist” Documentary
Opening music “Wishful Thinking” by Dan Lebowitz; montage music “Cartoon Bank Heist” by Doug Maxwell Media Right Productions
…and thank you Mom, my greatest teacher.
More reading: Project CBD
“World Health Organization Recommends Reclassifying Marijuana Under International Treaties” Forbes 2/1/2019 article
[Full description including glossary link to website]
[FTA] “…Initial trials of herbal cannabis for AD have begun sporadically, with a more focused effort in a California nursing home (Hergenrather, 2017). Patients were treated with a variety of preparations: THC-predominant (2.5–30 mg/dose), CBD predominant, and THCA, mainly in tinctures and confections. Marked benefit was reported on neuroleptic drug sparing, decreased agitation, increased appetite, aggression, sleep quality, objective mood, nursing care demands, self-mutilation and pain control.
Based on its pharmacology (Russo and Marcu, 2017), cannabis components may provide myriad benefits on target symptoms in this complex disorder:
• Agitation: THC, CBD, linalool
• Anxiety: CBD, THC (low dose), linalool
• Psychosis: CBD
• Insomnia/Restlessness: THC, linalool
• Anorexia: THC
• Aggression: THC, CBD, linalool
• Depression: THC, limonene, CBD
• Pain: THC, CBD
• Memory: alpha-pinene (Russo, 2011; Russo and Marcu, 2017) + THC
• Neuroprotection: CBD, THC
• Reduced Aβ plaque formation: THC, CBD, THCA
Thus, an extract of a Type II chemovar of cannabis (THC/CBD) with a sufficient pinene fraction would seem to be an excellent candidate for clinical trials (Lewis et al., 2018).”
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