Role of Cannabis and Endogenous Cannabinoids in Cancer
Dr Silvia Marino MSc. PhD.
University of Sheffield, United Kingdom
The majority of deaths from cancer following conventional therapies are a result of metastases. The endocannabinoid system is involved in the regulation of a variety of physiological processes including inflammation, bone metabolism and cancer. Dr Marino’s work will build on our group previous work on the role of the endocannabinoid system in bone, and attempt to establish whether small molecule inhibitors that selectively target and inhibit the endocannabinoid system might be of value in the treatment of advanced cancer. This addresses a huge unmet clinical need, as metastasis and acquired resistance to conventional anti-cancer therapy are major clinical problems in cancer patients with bone metastasis.